Figure 3.

The concordance rate of mNGS and culture was 56.8%, and additional 28.8% mNGS positive were detected in culture negative samples and it differed in sample types. mNGS, metagenomic next-generation sequencing. Others included 17 CSF, 16 swab, 10 secretion, 10 bone marrow, 4 bile, 4 urine, 2 paraffin section and 1 saliva. BALF, bronchoalveolar lavage fluid; mNGS+, metagenomic next-generation sequencing positive for Mycobacterium tuberculosis complex; P, pulmonary sample; EP, extrapulmonary samples; tissue-P, lung tissue; tissue-EP, extrapulmonary tissue; BALF, bronchoalveolar lavage fluid; mNGS, metagenomic next-generation sequencing.