Table 1. Clinicopathologic variables and univariate analysis of the Chinese training cohort of node-negative stage III gastric cancer patients.
Population | No. of patients | 3-year OS (%) |
5-year OS (%) |
Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|---|---|
P value | HR (95% CI) | P value | |||||
Gender | 0.456 | ||||||
Female | 18 | 27.8 | 16.8 | ||||
Male | 66 | 40.9 | 22.7 | ||||
Age, years | 0.016 | 0.049 | |||||
≤60 | 40 | 50 | 27.5 | 1 (Ref.) | |||
>60 | 44 | 27.3 | 15.9 | 1.720 (1.013–2.961) | |||
Tumor size, cm | 0.006 | 0.034 | |||||
≤4 | 19 | 63.2 | 47.7 | 1 (Ref.) | |||
>4 | 65 | 30.8 | 13.8 | 2.012 (1.006–4.024) | |||
Tumor location | 0.854 | ||||||
Upper third | 26 | 38.5 | 23.2 | ||||
Middle third | 16 | 31.3 | 18.8 | ||||
Lower third | 29 | 44.8 | 24.1 | ||||
>2/3 stomach | 13 | 30.8 | 15.4 | ||||
Lauren classification | 0.034 | 0.265 | |||||
Intestinal | 43 | 44.2 | 30.2 | 1 (Ref.) | |||
Diffuse | 41 | 31.7 | 12.2 | 1.344 (0.800-2.258) | |||
Type of gastrectomy | 0.016 | 0.042 | |||||
TG | 33 | 15.2 | 12.1 | 1 (Ref.) | |||
DG | 35 | 48.6 | 22.9 | 0.542 (0.302-0.972) | |||
PG | 16 | 62.5 | 37.5 | 0.450 (0.213-0.951) | |||
ELNs | <0.001 | <0.001 | |||||
ELNs ≤31 | 55 | 21.8 | 5.5 | 1 (Ref.) | |||
ELNs >31 | 29 | 69.0 | 51.7 | 0.235 (0.125–0.444) |
No., number; OS, overall survival; HR, hazard ratio; 95% CI, 95% confidence interval; Ref, reference; TG, total gastrectomy; PG, proximal gastrectomy; DG, distal gastrectomy; ELNs, examined lymph nodes.