Table 2. Clinicopathologic variables and univariate analysis of the SEER cohort of node-negative stage III gastric cancer patients.
| Population | No. of patients | 3-year OS (%) | 5-year OS (%) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|---|
| P value | HR (95% CI) | P value | |||||
| Gender | 0.913 | ||||||
| Female | 76 | 35.0 | 29.8 | ||||
| Male | 120 | 36.8 | 30.1 | ||||
| Age, years | 0.011 | 0.008 | |||||
| ≤60 | 66 | 45.5 | 40.3 | 1 (Ref.) | |||
| >60 | 130 | 30.8 | 26.9 | 1.584 (1.105–2.269) | |||
| Tumor size, cm | 0.184 | 0.591 | |||||
| ≤4 | 42 | 38.1 | 33.2 | 1 (Ref.) | |||
| >4 | 120 | 37.5 | 34.8 | 1.006 (0.701–1.020) | |||
| unknown | 34 | 26.5 | 17.6 | 1.283 (0.775–2.124) | |||
| Tumor location | 0.570 | ||||||
| Upper third | 23 | 26.1 | 21.7 | ||||
| Middle third | 24 | 45.8 | 41.7 | ||||
| Lower third | 86 | 36.0 | 30.9 | ||||
| >2/3 stomach | 31 | 32.3 | 22.6 | ||||
| Unknown | 32 | 37.5 | 33.8 | ||||
| Lauren classification | 0.120 | 0.216 | |||||
| Intestinal | 65 | 41.5 | 34.9 | 1 (Ref.) | |||
| Diffuse | 125 | 31.2 | 28.0 | 1.284 (0.896-1.840) | |||
| unknown | 6 | 66.7 | 50.0 | 0.671 (0.191-1.998) | |||
| ELN | 0.017 | 0.010 | |||||
| ELN ≤31 | 180 | 33.0 | 29.0 | 1 (Ref.) | |||
| ELN >31 | 16 | 71.4 | 64.3 | 0.421 (0.184–0.964) | |||
No., number; OS, overall survival; HR, hazard ratio; 95% CI, 95% confidence interval; Ref, reference; ELNs, examined lymph nodes; SEER, Surveillance, Epidemiology, and End Results..