Table 3. Adverse reactions and cytokine of levels after treatment.
| Patient No. | Highest temperature (°C) | Fever duration (d) | Maximum copy amount (×105) | Peak amplification time (d) | No. of CAR positive T Cells Infused (×106/kg) | Toxicities | |
|---|---|---|---|---|---|---|---|
| CRS (grade and feature) | CRES (grade and feature) | ||||||
| P007 | 39.8 | 6 | 1.200 | 7 | 1.8 | 2 (fever, hypotension, vomiting chills) | 3 (convulsion, confusion) |
| P011 | 39.5 | 6 | 1.805 | 7 | 2.0 | 1 (fever, sore muscles) | 0 |
| P014 | 38.9 | 7 | 0.750 | 11 | 1.0 | 2 (fever, chilsl, emesis) | 0 |
| P016 | 38.5 | 6 | 2.950 | 7 | 2.0 | 2 (fever, weak, loss of appetite) | 2 (dysphoria, delirium) |
| P018 | 39.9 | 3 | 1.200 | 7 | 2.0 | 1 (fever) | 1 (confusion, delays in response) |
| P025 | 39.8 | 8 | 1.014 | 11 | 2.0 | 1 (fever) | 0 |
| P032 | 39.0 | 7 | 0.077 | 7 | 2.0 | 1 (fever) | 0 |
| P040 | 39.0 | 9 | 0.131 | 10 | 3.0 | 2 (fever, lung infection) | 0 |
| P108 | 38.3 | 6 | 0.783 | 7 | 2.0 | 1 (fever) | 0 |
| P185 | 37.1 | 0 | 0.127 | 10 | 3.0 | 0 | 0 |
| P189 | 37.9 | 3 | 0.935 | 10 | 3.0 | 1 (fever) | 0 |
CAR, chimeric antigen receptor; CRS, cytokine release syndrome; CRES, CART-cell-related encephalopathy syndrome.