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. 2020 Sep;8(18):1161. doi: 10.21037/atm-20-5832

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Abundance analysis of differential florae between the different groups of cervical scraping samples. Differential florae with significant differences in abundance were estimated by linear discriminant analysis (LDA) effect size analysis. The length of the histogram represents the magnitude of the impact of significantly different species. (A) Abundance analysis of the microbiota between high-risk human papillomavirus (HPV) persistent infection with higher-grade squamous intraepithelial lesion (HSIL) and the high-risk HPV persistent infection with lower-grade squamous intraepithelial lesion (LSIL) group. (B) Abundance analysis of the microbiota between the high-risk HPV persistent infection with LSIL group and high-risk HPV transient infection with HSIL group. (C) Abundance analysis of the microbiota between high-risk HPV transient infection with HSIL group and high-risk HPV transient infection with LSIL group. (D) Abundance analysis of the microbiota between high-risk HPV transient infection with LSIL group and the non-infected HPV group. (E) Abundance analysis of the microbiota between high-risk HPV persistent infection with HSIL and the non-infected HPV group.