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. 2020 Oct 20;6:107. doi: 10.1038/s41420-020-00342-7

Fig. 6. ERK5 is required for differentiation and mitophagy in erythroid progenitors.

Fig. 6

a Murine erythroid progenitors were treated with XMD8–92 (5 μM) or vehicle control (DMSO) prior to initiation of differentiation. Levels of CD71 and Ter119 were measured by flow cytometry. Representative profiles are shown. b Mitochondrial mass was quantified in Ter119+CD71high and Ter119+CD71low erythroblasts using median fluorescence intensity (MFI) of MitoTracker Deep Red FM. The data represent three replicates. *P < 0.05; **P < 0.01; ***P < 0.001.