FIGURE 6.

DHTS sensitizes A2780 ovarian cancer cells to cisplatin by inducing DNA damage. (A) Anti‐proliferative effect of different compounds in A2780 cells by MTT assay. Cell lines were treated with DMSO (control), DHTS (2 μM), cisplatin (6 μM) or a combination of DHTS and cisplatin for 48 h. (B) Levels of cellular γH2AX foci in A2780 cancer cells by immunofluorescence. A2780 cells were treated with different agents for 24 h, followed by γ‐H2AX antibody staining. Bar scale = 50 μm, *P < .05 and **P < .01 vs. untreated control