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. 2020 Aug 26;24(19):11254–11271. doi: 10.1111/jcmm.15692

FIGURE 8.

FIGURE 8

The molecular mechanism of MSC‐derived EVs carrying miR‐27b in affecting cutaneous wound healing through the ITCH/JUNB/IRE1α axis. MSC‐derived EVs carrying miR‐27b suppressed the ITCH expression in HaCaT cells and HSFs, and consequently enhanced the expression of JUNB, and IRE1α, thus improving the proliferation and migration of HaCaT cells and HSFs and accelerating the cutaneous wound healing in mice