FIGURE 7.

Dysregulation of TLR4, IL‐1b, TNF‐a, NF‐kB, HMGB1 and IL‐10 in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA (*P value < 0.05 vs NC group; **P value < 0.05 vs I/R group). A, Abnormal elevation of TLR4 expression in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA. B, Abnormal elevation of IL‐1b expression in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA. C, Abnormal elevation of TNF‐a expression in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA. D, Abnormal elevation of NF‐kB expression in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA. E, Abnormal elevation of HMGB1 expression in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA. F, Abnormal repression of IL‐10 expression in I/R rats was restored to normal by combined treatment with MSC‐derived exosomes and GA