Figure 8.

Overexpression of lnc‐NOS2P3 promoted inflammation‐induced apoptosis which was rescued by miR‐939‐5p mimic. A, 800 ng lnc‐NOS2P3‐WT or lnc‐NOS2P3‐mut and vector control were transfected into HUVECs with 100 nM miR‐939‐5p or mimic control. CCK8 assay showed its proliferation 48 hours later. B and C, 800 ng lnc‐NOS2P3‐WT (WT) or lnc‐NOS2P3‐mut (Mut) and their vector control (NC) were transfected with 100 nM miR‐939‐5p mimic (939 mm) or its mimic control (mm). B, Flow cytometry showed the apoptosis cells ratios, and data were analysed statistically. C, Apoptosis related proteins were measured by Western blot. Data are mean ± SEM. *P < 0.05 and **P < 0.01