FIGURE 4.

RAGE regulates hepatic FFA mitochondrial β‐oxidation in vitro. (a) PPARα expression was determined by real‐time PCR and Western blot analysis in the primary hepatocytes transfected with RAGE siRNA or control siRNA. (b–g) After the primary hepatocytes were transfected with RAGE siRNA or NC siRNA and stimulated with OA/PA or the BSA control, the cellular TGs (b), expression levels of PPARα (c), CPT1a, CPT1b, and MCAD (d), intact cellular oxygen consumption rate in real time (e), cellular ATP levels (f), and copy numbers of MT‐CYB and 12S rRNA (g) were examined