Table 1.
Detailed information of 63 core targets.
| NO. | Target name | Degree centrality | Betweenness centrality | Closeness centrality |
|---|---|---|---|---|
| 1 | ALB | 132 | 0.10194051 | 0.57963875 |
| 2 | SREBF1 | 101 | 0.04648343 | 0.54058193 |
| 3 | APOB | 88 | 0.02798912 | 0.52373887 |
| 4 | APOE | 87 | 0.03066411 | 0.52765321 |
| 5 | PPARγ | 84 | 0.02496889 | 0.53082707 |
| 6 | MAPK3 | 82 | 0.03803816 | 0.52923538 |
| 7 | HMGCR | 79 | 0.02839721 | 0.51911765 |
| 8 | EGF | 77 | 0.0326961 | 0.51683748 |
| 9 | LDLR | 74 | 0.01786479 | 0.5 |
| 10 | FASN | 74 | 0.01620772 | 0.502849 |
| 11 | PPARA | 74 | 0.01758367 | 0.5130814 |
| 12 | PTGS2 | 73 | 0.03636725 | 0.50573066 |
| 13 | SREBF2 | 72 | 0.02642683 | 0.4862259 |
| 14 | APP | 68 | 0.02026671 | 0.50500715 |
| 15 | LEP | 67 | 0.01366234 | 0.50864553 |
| 16 | ABCA1 | 66 | 0.02050839 | 0.49509116 |
| 17 | SCD | 66 | 0.01940855 | 0.48891967 |
| 18 | APOA1 | 65 | 0.0104694 | 0.48891967 |
| 19 | CAT | 59 | 0.0231604 | 0.50070922 |
| 20 | ADIPOQ | 59 | 0.01236963 | 0.49788434 |
| 21 | CYP3A4 | 59 | 0.01670894 | 0.48356164 |
| 22 | ESR1 | 58 | 0.0240653 | 0.49509116 |
| 23 | DGAT1 | 54 | 0.00895186 | 0.47446237 |
| 24 | CYP2B6 | 53 | 0.01261496 | 0.48422497 |
| 25 | APOC3 | 51 | 0.00521994 | 0.45844156 |
| 26 | ACACA | 51 | 0.0040295 | 0.47638327 |
| 27 | CREB1 | 51 | 0.01442992 | 0.49164345 |
| 28 | SIRT1 | 50 | 0.01736748 | 0.49301676 |
| 29 | MAPK14 | 48 | 0.00877424 | 0.47702703 |
| 30 | FABP1 | 48 | 0.01145724 | 0.46693122 |
| 31 | CAV1 | 48 | 0.01458166 | 0.48092643 |
| 32 | SQLE | 47 | 0.00778386 | 0.44853875 |
| 33 | AGT | 47 | 0.00760543 | 0.47510094 |
| 34 | CLU | 47 | 0.00773464 | 0.45844156 |
| 35 | LIPE | 47 | 0.00794991 | 0.47638327 |
| 36 | FADS1 | 47 | 0.00692009 | 0.45607235 |
| 37 | LIPC | 46 | 0.00999712 | 0.44968153 |
| 38 | CYP2E1 | 46 | 0.01342474 | 0.4738255 |
| 39 | IL4 | 45 | 0.00870765 | 0.47192513 |
| 40 | ACOX1 | 45 | 0.0035187 | 0.45784695 |
| 41 | HMGCS1 | 44 | 0.00325402 | 0.44853875 |
| 42 | ACLY | 44 | 0.01071917 | 0.46083551 |
| 43 | CYP19A1 | 44 | 0.01030837 | 0.47255689 |
| 44 | CYP2C9 | 44 | 0.00700349 | 0.46754967 |
| 45 | SCARB1 | 44 | 0.00915057 | 0.47003995 |
| 46 | FDFT1 | 43 | 0.00425437 | 0.45140665 |
| 47 | DGAT2 | 43 | 0.00166345 | 0.44291092 |
| 48 | APOA4 | 43 | 0.00578781 | 0.45314506 |
| 49 | CD44 | 43 | 0.01055526 | 0.46816976 |
| 50 | CYP51A1 | 41 | 0.00425467 | 0.44180225 |
| 51 | HSD3B1 | 41 | 0.00690686 | 0.44180225 |
| 52 | DHCR7 | 41 | 0.00378824 | 0.42891859 |
| 53 | PON1 | 41 | 0.00478681 | 0.46693122 |
| 54 | LSS | 40 | 0.00646986 | 0.44570707 |
| 55 | ACE | 40 | 0.00407366 | 0.47255689 |
| 56 | ABCG2 | 40 | 0.02206365 | 0.46816976 |
| 57 | F2 | 39 | 0.00736964 | 0.47319035 |
| 58 | KRAS | 39 | 0.00749875 | 0.46143791 |
| 59 | LCAT | 39 | 0.00395196 | 0.46204188 |
| 60 | NR3C1 | 39 | 0.00692536 | 0.47003995 |
| 61 | FABP4 | 38 | 0.0045635 | 0.44796954 |
| 62 | ABCB1 | 38 | 0.01106088 | 0.46693122 |
| 63 | HNF4A | 38 | 0.01122196 | 0.47574124 |