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. 2020 Oct 20;3(10):e2021457. doi: 10.1001/jamanetworkopen.2020.21457

Table 5. Logistic Regression Associations Between Covariates of Interest and 180-Day Hospital Admission, by Model Type (N = 4685).

Covariates Odds ratio (95% CI)a
Model with EHR-based covariates Model with EHR- and survey-based covariates, forward-selected
All Forward-selected
EHR-based measure
Demographic characteristic
Age, y
<60 1 [Reference]
60-80 0.88 (0.65-1.19)
>80 0.76 (0.51-1.11)
Sex
Male 1 [Reference]
Female 0.75 (0.47-1.19)
Race/ethnicity
Non-Hispanic White 1 [Reference]
Non-Hispanic Black 0.97 (0.74-1.28)
Hispanic 1.06 (0.66-1.69)
Other 1.28 (0.71-2.31)
VA copay status
Exempt 1 [Reference] 1 [Reference] 1 [Reference]
Nonexempt 0.69 (0.50-0.97) 0.69 (0.50-0.96) 0.72 (0.52-1.01)
Residence
Nonrural 1 [Reference] 1 [Reference] 1 [Reference]
Rural 0.85 (0.69-1.05) 0.85 (0.69-1.05) 0.86 (0.70-1.06)
Chronic health condition
Gagne comorbidity scoreb
For 1-unit increase (when initial score in −2 to 0 range) 0.95 (0.63-1.44) 0.96 (0.63-1.46) 0.97 (0.64-1.47)
For 1-unit increase (when initial score in 1 to 13 range) 1.11 (0.72-1.70) 1.11 (0.72-1.70) 1.14 (0.74-1.77)
Non-Gagne health conditions (presence vs absence [reference])
Anxiety 0.94 (0.71-1.26)
Bipolar disorder 1.46 (0.90-2.35) 1.44 (0.91-2.28) 1.44 (0.90-2.29)
Dyslipidemia 0.99 (0.81-1.20)
Posttraumatic stress disorder 0.88 (0.68-1.14)
Schizophrenia 1.70 (0.98-2.95) 1.75 (1.01-3.01) 1.71 (0.98-2.96)
Traumatic brain injury 1.08 (0.22-5.24)
Spinal cord trauma 1.72 (0.69-4.31)
Other clinical characteristic
BMI
<25 1 [Reference]
25 to <30 0.94 (0.71-1.26)
30 to <35 0.93 (0.69-1.26)
≥35 1.03 (0.76-1.41)
Frailty (JEN Frailty Index, for 1-unit increase) 1.21 (1.14-1.28) 1.21 (1.14-1.28) 1.21 (1.14-1.28)
Alcohol use (AUDIT-C score)
None (0) 1 [Reference] 1 [Reference] 1 [Reference]
Low (1-2 [female], 1-3 [male]) 0.89 (0.71-1.12) 0.90 (0.72-1.13) 0.90 (0.71-1.14)
Moderate (3-7 [female], 4-7 [male]) 1.30 (0.92-1.84) 1.33 (0.94-1.87) 1.32 (0.94-1.87)
High (>7) 1.56 (0.88-2.74) 1.65 (0.94-2.87) 1.63 (0.93-2.85)
Survey-based measure
Workload domain
Physical function: limitations in activities of daily living (for a 1-unit increase) 1.06 (0.99-1.13)
Chaotic lifestyle score 1.03 (1.00-1.06)
Capacity/resilience domain
Low resilience, score
>3 1 [Reference]
≤3 0.81 (0.65-1.02)
Married
No 1 [Reference]
Yes 0.75 (0.62-0.92)
Preference/expectations
Powerful others health-related locus of control (score)
≤18 1 [Reference]
>18 to 22 1.05 (0.84-1.30)
>22 to 30 0.78 (0.59-1.03)
Mean AIC (SD) 2981.9 (2.8) 2961.31(2.5) 2951.9 (2.2)

Abbreviations: AIC, Akaike Information Criterion; AUDIT-C, Alcohol Use Disorders Identification Test; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); EHR, electronic health record; VA, Veterans Affairs.

a

Calculated using PROC MIANALYZE within SAS software, version 9.4, to combine estimates from 10 imputed data sets (SAS PROC MI) per model type. Although the primary analyses were not based on statistical significance, the 95% CIs are provided to inform uncertainty around the magnitude of the estimates from the covariates selected as improving estimates of the outcomes based on AIC.

b

Gagne score was included in the model as a piecewise continuous variable comprised of 2 pieces, one for Gagne scores with initial value of −2 to 0 and the other for Gagne scores with initial values of 1 to 13. The reported Gagne odds ratios and 95% CIs are for a 1-unit increase in the Gagne score.