Figure 3.

Two-dimensional grids (glucose on the y-axis and C-peptide on the x-axis) showing the GCRCs from 30 to 120 min and their centroid comparisons (comparison of the central location for each plot) for nonprogressors with GRCs that changed from monophasic to biphasic from first to last OGTT (A), progressors with GRCs that changed from monophasic to monotonic from last to diagnostic OGTTs (B), and progressors with GRCs that remained monophasic from last to diagnostic OGTTs (C). Arrows in each panel point to the change in location of the centroid locations on the grid. *Mean values for glucose and C-peptide at the different time points (30–120 min) during the OGTT.