Table 2.

Predictors of reduction in SU at 24 months: multivariable regression model

	All (n = 235)		Participants without diabetes* (n = 201)
Variable in the models	β	P value	β	P value
Baseline SU, μmol/L (mg/dL)	−28.6 (−0.48)	<0.001	−29.7 (−0.50)	<0.001
Weight loss at 24 months (kg)	0.04	<0.001	0.03	0.03
Fasting plasma insulin reduction at 24 months (pmol/L)	NA	NA	0.21	0.21
Age (years)	−0.01	0.47	0.002	0.85
Male sex	0.66	0.001	0.82	<0.001
Mediterranean diet vs. low-fat assigned diet	0.15	0.32	0.16	0.32
Low-carbohydrate vs. low-fat assigned diet	0.03	0.87	0.02	0.88

NA, not applicable.

^*Limited to participants without diabetes because insulin concentration is affected by diabetes or antidiabetic medications.