Table 2.

Relevant cost factors as well as sources and descriptions.

Cost factor	Costsa	Reasons and description
Device costs	€437.65	The price was derived from the most popular PPGb AFc screening device, the Apple Watch Series 5 [12]. An integrated algorithm diagnoses AF automatically. Trained personnel for interpretation is not needed.
Visit to the doctor and diagnostics	€67.23	Physician visit: ordination and consultation, €13.20; urgent care, €12.90; and telemedical care, €9.52. Diagnostics: long-term ECG and 12-lead ECG, €9.96; stress ECG, €21.65; derived from the study of McBride et al [13] and adapted to current conditions [14].
Medication costs for oral anticoagulation (NOACd)	€1226	The use of rivaroxaban was assumed because it is the most prescribed NOAC in Germany [15].e
Per year costs incurred after surviving a stroke	€15,753 (year 1), €4480 (year 2)… €1481 (year 10)	Interpolation and extrapolation of costs derived from the study of Kolominsky-Rabas et al [16] (Figure 3).e
Costs for major bleeding	€1995	Directly derived from the study of Reinhold et al [6].
Annual discounting rate	3%	Own assumption.

^a€1=US $1.12.

^bPPG: photoplethysmography.

^cAF: atrial fibrillation.

^dNOAC: non–vitamin K antagonist.

^eThe program was realized using unrounded amounts in Euro.