Table 1.
Host characteristics of SRRSH and TCGA cohorts.
| Variables/biomarkers | SRRSH | TCGA |
|---|---|---|
| All casesa | 291 | 279 |
| Age | ||
| Mean (SD) | 59.7 (11.6) | 65.8 (10.6) |
| Range | 29–80 | 29–80 |
| ≤60 | 133 | 81 |
| >60 | 158 | 193 |
| Sex | ||
| Male | 207 | 179 |
| Female | 84 | 100 |
| TNM stage | ||
| II | 111 | 117 |
| III | 180 | 162 |
| Tumor gradeb | ||
| Low | 35 | 6 |
| Medium | 71 | 81 |
| High | 185 | 192 |
| Histology | ||
| Papillary | 4 | NA |
| Mucinous | 24 | NA |
| Signet ring cell | 30 | NA |
| Poor differentiation | 231 | NA |
| Tumor location | ||
| Proximal | 61 | NA |
| Body | 63 | NA |
| Distal | 156 | NA |
| Linitis plastica | 11 | NA |
| Tumor size | ||
| <5cm | 108 | NA |
| ≥5cm | 174 | NA |
| Chemotherapy | ||
| Yes | 173 | 146 |
| No | 118 | 133 |
a
Among all biomarkers, there are part of patients' expression information missing: 49 patients in RRM1,48 patients in RRM2, 46 patients in RRM2B, 49 patients in POLH, 47 patients in DUTPASE, 48 patients in KI-67, 46 patients in TYMS and 39 patients in TYMP in SRRSH cohort; In TCGA dataset, age information in 5 cases were missing.
b
33 cases in the SRRSH cohort and 4 cases in the TCGA cohort are undifferentiated, which were included in high tumor grade.