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Single-turnover kinetic values for tcTERT single nucleotide insertion.
| Incoming nucleotide | kpol (s−1) | Kd (μM) | Catalytic efficiency (kpol/Kd) (μM−1 s−1) | Fold change |
|---|---|---|---|---|
| dGTPa | 1.1 ± 0.03 | 18.1 ± 3.78 | 0.058 ± 0.012 | 1.000 |
| 6-thio-dGTP | 3.1 ± 0.23 | 92.4 ± 12.94 | 0.034 ± 0.005 | 0.579 |
aValues from ref. 43.
