Table 3.
Univariate and multivariate analysis for thirty-day clinical cure in E. coli bacteremic urinary tract infections
| Variable | Unadjusted Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age (per year) | 0.98 (0.93–1.02) | 0.30 | … | … |
| Sex (female) | 2.49 (0.60–10.30) | 0.21 | … | … |
| DM | 0.29 (0.07–1.22) | 0.09 | 0.50 (0.08–3.04) | 0.45 |
| CKD | 0.18 (0.03–0.97) | 0.046 | 0.28 (0.03–3.06) | 0.30 |
| Heart Conditions | 0.18 (0.02–1.49) | 0.11 | 0.38 (0.03–4.43) | 0.44 |
| Asthma/COPD | 0.78 (0.09–6.69) | 0.82 | … | … |
| Immunocompromised | 0.29 (0.03–2.68) | 0.28 | … | … |
| Recurrent UTI risk factors | 0.12 (0.02–0.63) | 0.01 | 0.15 (0.02–0.96) | 0.045 |
| CA-UTI | 0.33 (0.04–2.99) | 0.33 | … | … |
| Charlson (per unit) | 0.69 (0.52–0.92) | 0.01 | 0.71 (0.41–1.21) | 0.20 |
| Pitt (per unit) | 0.72 (0.49–1.04) | 0.08 | 0.66 (0.39–1.10) | 0.11 |
| Sepsis | 0.61 (0.14–2.62) | 0.50 | … | … |
| Septic Shock | 0.45 (0.05–3.95) | 0.47 | … | … |
| ICU admission | 0.49 (0.05–4.28) | 0.52 | … | … |
| Beta-lactam allergy | 0.34 (0.06–1.77) | 0.20 | 0.14 (0.02–1.14) | 0.07 |
| IV therapy duration | 0.83 (0.67–1.03) | 0.09 | 0.88 (0.65–1.18) | 0.40 |
| Total duration | 1.01 (0.80–1.27) | 0.96 | … | … |
| Oral beta-lactam step down | 0.34 (0.08–1.47) | 0.15 | 0.31 (0.05–1.90) | 0.21 |
Abbreviations: CA-UTI catheter-associated urinary tract infection, CKD chronic kidney disease, CI confidence interval, COPD chronic obstructive pulmonary disease, DM diabetes mellitus, ICU intensive care unit, IV intravenous, OR odds ratio, UTI urinary tract infection