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. 2020 Oct 20;10:17786. doi: 10.1038/s41598-020-74810-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Kaplan–Meier curves for disease-specific survival (DSS) and progression-free survival (PFS) based on cytoplasmic Talin1 protein expression level in CRC patients. (A) In CRC patients, lower level of Talin1 protein expression was associated with shorter DSS compared to the tumors with high expression of this protein (P = 0.048). (B) Kaplan–Meier survival analysis showed that low levels of Talin1 protein expression are not significantly related to PFS (P = 0.079).