Table 5.
Comparison of baseline characteristics between the patients with EP ( +) and EP (−) after re-RT
| Variables | EP (−) | EP ( + ) | p |
|---|---|---|---|
| Re-RT age (years) (n, %) | 0.693 | ||
| ≤ 60 | 68 (34.3) | 17 (31.5) | |
| > 60 | 130 (65.7) | 37 (68.5) | |
| Gender (n, %) | 0.955 | ||
| Male | 162 (81.8) | 44 (81.5) | |
| Female | 36 (18.2) | 10 (18.5) | |
| Smoking (n, %) | 0.965 | ||
| Yes | 96 (48.5) | 26 (48.1) | |
| No | 102 (51.5) | 28 (51.9) | |
| Alcohol consumption (n, %) | 0.206 | ||
| Yes | 80 (40.4) | 27 (50) | |
| No | 118 (59.6) | 27 (50) | |
| Primary tumor location (n, %) | |||
| Upper | 53 (26.8) | 19 (35.2) | 0.225 |
| Middle and lower thoracic | 145 (73.2) | 35 (64.8) | |
| Length, cm (n, %) | 0.872 | ||
| ≤ 4 | 121 (61.1) | 31 (57.4) | |
| 4 < to ≤ 6 | 55 (27.8) | 16 (29.6) | |
| > 6 | 22 (11.1) | 7 (13.0) | |
| Ulcerative type (n, %) | 0.546 | ||
| Yes | 109 (55.1) | 25 (46.3) | |
| No | 89 (44.9) | 29 (53.7) | |
| Tumor differentiation (n, %) | 0.882 | ||
| Higher | 29 (14.6) | 7 (13.0) | |
| Middle | 113 (57.1) | 30 (55.6) | |
| Lower | 56 (28.3) | 17 (31.4) | |
| T stage (n, %) | 0.962 | ||
| T1–2 | 63 (31.8) | 17 (31.5) | |
| T3–4 | 135 (61.2) | 37 (68.5) | |
| Initial clinical/pathological stage (n, %) | 0.775 | ||
| I–II | 91 (46.0) | 26 (48.1) | |
| III–Iva | 107 (54) | 28 (51.9) | |
| Initial treatment (n, %) | 0.171 | ||
| RT | 127 (64.1) | 40 (74.1) | |
| Surgery + RT | 71 (35.9) | 14 (25.9) | |
| Pattern of recurrence (n, %) | 0.010 | ||
| Regional lymph node recurrence only | 90 (45.4) | 15 (27.8) | |
| Local failure | 73 (36.9) | 20 (37.0) | |
| Both | 35 (17.7) | 19 (35.2) | |
| Recurrence-free interval (months) (n, %) | 0.025 | ||
| ≤ 12 | 53 (36.8) | 23 (42.6) | |
| > 12 | 145 (73.2) | 31 (57.4) | |
| Re-RT dose (Gy) (n, %), BED10 | 0.442 | ||
| ≤ 60 | 102 (51.5) | 31 (53.7) | |
| > 60 | 96 (48.5) | 23 (46.3) | |
| Concurrent chemoradiotherapy (n, %) | 0.894 | ||
| Yes | 86 (43.4) | 24 (44.4) | |
| No | 112 (56.6) | 30 (55.6) | |
| Total radiation dose (Gy) (n, %), BED10 | 0.334 | ||
| ≤ 131.5 | 99 (50.0) | 31 (57.4) | |
| > 131.5 | 99 (50.0) | 23 (42.6) | |
| Esophageal stenosis (n, %) | 0.000 | ||
| Yes | 68 (34.3) | 34 (63.0) | |
| No | 130 (65.7) | 20 (37.0) | |
| Fat space between tumor and adjacent tissue disappeared (n, %) | 0.000 | ||
| Yes | 37 (18.7) | 27 (50.0) | |
| No | 161 (81.3) | 27 (50.0) | |
| Pain in the chest or/and back (n, %) | 0.175 | ||
| Yes | 17 (8.6) | 8 (14.8) | |
| No | 181 (91.4) | 46 (85.2) | |
| Median BMI (n, %) | 0.102 | ||
| ≤ 20 | 63 (31.8) | 11 (20.4) | |
| > 20 | 135 (68.2) | 43 (79.6) | |
| Hemoglobin (n, %) | 0.141 | ||
| ≤ 12 | 70 (35.4) | 25 (46.3) | |
| > 12 | 128 (64.6) | 29 (53.7) | |
| Albumin (n, %) | 0.447 | ||
| ≤ 40 | 66 (33.3) | 21 (38.9) | |
| > 40 | 132 (66.7) | 33 (61.1) | |
| White blood cells, × 109/L | 5.776 ± 2.285 | 6.520 ± 3.103 | 0.059 |
| Neutrophil, × 109/L | 4.379 ± 2.172 | 5.013 ± 2.936 | 0.090 |