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. 2020 Oct 20;16:397. doi: 10.1186/s12917-020-02612-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Effects of ivermectin cream on cutaneous wound tissue levels of MPO and hydroxyproline. Sprague-Dawley rats were anaesthetised and excision wounds created as described in the methods. Animals were sacrificed on either day 7 or day 21 post-wounding. The levels of myeloperoxidase on day 7 as well as levels of hydroxyproline on day 7 and day 21 were measured and presented as mean ± SEM. The statistical analysis for MPO levels was by One-Way ANOVA. * means p < 0.05, ** means p < 0.01,*** means p < 0.001 for treated groups when compared to the vehicle (naïve) control group. The statistical analysis for hydroxyproline was by Two-Way ANOVA followed by Bonferroni's post hoc test. * means p < 0.05,** means p < 0.01 when compared to the corresponding day control levels whilst # means p < 0.05, ## means p < 0.01, #### means p < 0.0001 when comparing levels on day 7 to day 21 within a group