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. 2020 Oct 20;16:397. doi: 10.1186/s12917-020-02612-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Effects of ivermectin cream on cutaneous wound levels of TGF-B1 and VEGF. Sprague Dawley rats were anaesthetised and excision wounds created as described in the methods. Animals was sacrificed either on day 7 or day 21 post-wounding. The levels of TGF-ß1 on day 7 and day 21 as well as the levels of VEGF on day 7 and day 21 were measured and presented as mean ± SEM. The statistical analysis was by Two-Way ANOVA. Results shown as *p < 0.05,**p < 0.01,***p < 0.001, ****p < 0.0001, for all treated groups compared to vehicle (naïve) control group and # p < 0.05, ## p < 0.01, ### p < 0.001, #### p < 0.0001 represent comparison between levels on Day 7 and 21 within a group