Figure 1.

(a) Typical Medtronic 670G glucose profile when in Auto Mode with insulin delivery statistics. The left panel shows three characteristic days of the patient’s usual glucose profile (black lines are sensor glucose, small pink lines are automated insulin delivery every five minutes based on sensor glucose, and blue lines are meal related boluses taken by the patient) and the right panel shows sensor and insulin delivery statistics over 15 days from 3 months prior to his suicide. (b) Profile of insulin overdose event. The sensor glucose over time and insulin boluses on the day of suicide. The patient delivered a total of 180 U over 60 minutes between 8:45 and 9:45 am (blue lines). Based on his sensor glucose tracing (black line), we estimate that he may have become unconscious by around 10:45 am when his sensor glucose was undetectable. Insulin pump was delivering basal insulin (pink line) at rate of ~1.5 U/h despite his sensor glucose being undetectable.