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Expression of DNA damage response-related proteins following 2,3-DEPC treatment. (A) Expression level of p-Chk1 (Ser317 and Ser345) was markedly increased and (B) Cdc25Aexpression was markedly decreased following treatment with 20 µM 2,3-DCPE for 16, 24 and 32 h. 2,3-DCPE, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol; p-, phosphorylated; Chk, checkpoint kinase; Cdc25A, M-phase inducer phosphatase 1.
