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. 2020 Oct 20;7(1):e000430. doi: 10.1136/lupus-2020-000430

Table 2.

Conventional systemic drug alternatives to antimalarial therapy

Medication class Medication Evidence level*
Anti-inflammatory Isotretinoin 2B
Acitretin 2B
Dapsone 4
Thalidomide 2A
Lenalidomide 2B
Sulfasalazine 2B
Immunosuppressive Methotrexate 4
Mycophenolate mofetil (or mycophenolic acid) 2B
Azathioprine 4
Belimumab 2B
Blood product IVIG 2B

*Evidence levels adapted from the Oxford Centre for Evidence-Based Medicine.

IVIG, intravenous immunoglobulin.