Table I.
Mean IC50 values of CEP and TET on the cell viability of 2D monolayer MDA-MB-231 and MCF-7 cells.
| Drug | Cell line | 1×105 cells/ml | 2.5×105 cells/ml | 5×105 cells/ml |
|---|---|---|---|---|
| CEP | MDA-MB-231 | 3.8 | 5.4a | 8.6a |
| MCF-7 | 17.6 | 35.6 | 60.4 | |
| TET | MDA-MB-231 | 6.4 | 7.6 | 9.6a |
| MCF-7 | 13.5 | 26 | 84.7 |
IC50 values were calculated based on the sigmoidal curve of the cell viability using GraphPad Prism v8.0. The results are shown as the mean (µg/ml) of >3 independent experiments.
a
P<0.05 vs. the mean IC50 value of CEP or TET on MCF-7 cells analyzed via one-way ANOVA with a post-hoc Sidak's multiple comparisons test.