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. 2020 Sep 28;20(6):300. doi: 10.3892/ol.2020.12163

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Pathological changes of the liver in the control and B groups (magnification, ×20) on day 21 post-allogeneic hematopoietic stem cell transplantation displaying severe bile duct injury (red arrows) and lymphocyte infiltration (green arrows). Control group, blank control group; B1 group, severe GVHD group; B2 group, severe GVHD group with CTLA-4 intraperitoneal injection; B3 group, severe GVHD group with TIRC7 intraperitoneal injection; B4 group, severe GVHD group with CTLA-4 and TIRC7 intraperitoneal co-injection. Scale bar, 50 µm. aGVHD, acute graft-versus-host disease; TIRC7, T cell immune response cDNA 7; CTLA-4, cytotoxic T lymphocyte antigen-4.