TABLE 1.
Summary of demographics and baseline characteristics of study participantsa
| Characteristic | Value for: |
|||||
|---|---|---|---|---|---|---|
| Group 1 (3 mg/kg) | Group 2 (7.5 mg/kg) | Group 3 (15 mg/kg) | Group 4A (3 mg/kg, fasted → fed) | Group 4B (3 mg/kg, fed → fasted) | All subjects | |
| n | 8 | 8 | 8 | 6 | 6 | 36 |
| Age (yr) | 29.3 ± 9.1 (21.0–44.0) | 27.1 ± 6.1 (19.0–33.0) | 30.1 ± 4.4 (21.0–35.0) | 27.7 ± 5.6 (22.0–34.0) | 32.2 ± 9.4 (23.0–44.0) | 29.2 ± 6.9 (19.0–44.0) |
| Height (cm) | 178.0 ± 10.3 (163.5–195.6) | 173.5 ± 7.1 (165.0–184.0) | 170.8 ± 8.6 (160.0–184.0) | 173.9 ± 6.9 (166.0–184.5) | 174.1 ± 13.2 (158.5–196.0) | 174.1 ± 9.1 (158.5–196.0) |
| Weight (kg) | 88.9 ± 10.7 (76.8–103.0) | 78.4 ± 14.0 (56.8–97.0) | 76.9 ± 16.3 (58.6–104.0) | 82.6 ± 11.9 (69.8–105.0) | 86.3 ± 13.2 (73.2–105.0) | 82.4 ± 13.6 (56.8–105.0) |
| BMI (kg/m2) | 28.1 ± 2.6 (25.0–32.6) | 26.2 ± 5.3 (18.3–34.8) | 26.3 ± 5.3 (21.1–34.3) | 27.3 ± 4.0 (23.9–34.0) | 28.6 ± 4.0 (24.2–33.9) | 27.2 ± 4.2 (18.3–34.8) |
| Sex | ||||||
| Male | 7 (88) | 5 (63) | 4 (50) | 5 (83) | 4 (67) | 25 (69) |
| Female | 1 (13) | 3 (38) | 4 (50) | 1 (17) | 2 (33) | 11 (31) |
| Ethnicity | ||||||
| Not Hispanic or Latino | 7 (88) | 8 (100) | 7 (88) | 4 (67) | 6 (100) | 32 (89) |
| Hispanic or Latino | 1 (13) | 0 (0) | 1 (13) | 2 (33) | 0 (0) | 4 (11) |
| Race | ||||||
| Asian | 1 (13) | 1 (13) | 1 (13) | 1 (17) | 0 (0) | 4 (11) |
| Black or African-American | 0 (0) | 1 (13) | 0 (0) | 0 (0) | 0 (0) | 1 (3) |
| White | 7 (88) | 6 (75) | 6 (75) | 4 (67) | 6 (100) | 29 (81) |
| Multiracial | 0 (0) | 0 (0) | 1 (13) | 1 (17) | 0 (0) | 2 (6) |
a
Continuous variables are summarized as means ± SD (range); categorical variables are summarized as number (percentage) of patients.