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. 2020 Oct 20;64(11):e01463-20. doi: 10.1128/AAC.01463-20

TABLE 9.

ABI-H0731 cross-species liver microsome and hepatocyte stability^a

Species	Microsomes			Hepatocytes
Species	CL_pred (ml/min/kg)	T_1/2 (min)	% LBF	CL_pred (ml/min/kg)	T_1/2 (min)	% LBF
Human	2.8	376	13	2.3	695	11
Mouse	19	140	21	ND	ND	ND
Rat	7.9	277	12	21	105	32
Dog	20	37.3	65	25	40	81
Monkey	4.7	359	15	4.7	475	15

^a

ND, not determined; %LBF, percentage of liver blood flow.