TABLE 5.
Variability of Cyp51 and Fks1 genes in clinical L. prolificans isolates
| Gene or region | Characteristics of DNA sequences |
Characteristics of protein sequences |
|||
|---|---|---|---|---|---|
| Length (nt) | No. of SNPs | No. of allele types | Amino acid changesa | No. of protein types | |
| Cyp51 | 1,725 | 1 | 2 | 1 | |
| 5′ UTRb | 1,950 | 4 | 5 | ||
| Fks1 | 5,841 | 9 | 8 | D440A, S634R, H1245P | 4 |
a
5′ UTR, 5′ untranslated region of the Cyp51 gene (promoter region).
b
Amino acid changes compared with the protein sequence with the highest frequency of prevalence.