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. 2020 Oct 20;64(11):e01515-20. doi: 10.1128/AAC.01515-20

TABLE 2.

Oral step-down regimens

Regimena No. of patients No. of patients included in the high-dose group based on renal dosing adjustment
High dose
    Amoxicillin at 875 mg Q12H 2
    Amoxicillin at 1,000 mg Q8H 3
    Amoxicillin at 1,000 mg Q12H 1
    Amoxicillin-clavulanate at 875-125 mg Q12H 49
    Cefadroxil at 500 mg Q12H 3
    Cefadroxil at 1,000 mg Q12H 1
    Cefdinir at 300 mg Q12H 14
    Cefpodoxime at 200 mg Q12H 1
    Cefuroxime at 500 mg Q12H 5
    Cephalexin at 1,000 mg Q6H 3
    Cephalexin at 1,000 mg Q8H 4
    Levofloxacin at 750 mg Q24H 28
    Moxifloxacin at 400 mg Q24H 36
    Penicillin V at 500 mg Q6H 3
    Penicillin V at 500 mg Q8H 2
Low dose
    Amoxicillin at 500 mg Q8H 7
    Amoxicillin-clavulanate at 500-125 mg Q24H 2 2
    Amoxicillin-clavulanate at 500-125 mg Q12H 10 1
    Cefdinir at 300 mg Q24H 1 1
    Cephalexin at 500 mg Q6H 10
    Cephalexin at 500 mg Q8H 7
    Cephalexin at 500 mg Q12H 3 1
    Cephalexin at 1,000 mg Q12H 1
    Levofloxacin at 500 mg Q24H 16
    Levofloxacin at 500 mg Q48H 2 2
    Levofloxacin at 750 mg Q48H 5 5
    Penicillin V at 500 mg Q12H 1
a

QxH, every x hours.