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Death receptor activation downstream of clustering. Serial dilutions of death receptor targeted therapeutics were added to COLO 205 cells in the presence or absence of cross-linker. Viability was determined by Cell-titer glo after 24 h (a). Caspase-8 activity was determined by Caspase-glo 8 4 h following addition of therapeutics (b). The legend is shared for both graphs.
