TABLE 1.

Treatment algorithm for the management of acne vulgaris in adolescents and young adults4

MILD	MODERATE	SEVERE
First- line Treatment
Benzoyl Peroxide (BP) or Topical Retinoid -or- Topical Combination Therapy** BP + Antibiotic or Retinoid + BP or Retinoid + BP + Antibiotic	Topical Combination Therapy** BP + Antibiotic or Retinoid + BP or Retinoid + BP + Antibiotic -or- Oral Antibiotic + Topical Retinoid + BP -or- Oral Antibiotic + Topical Retinoid + BP + Topical Antibiotic	Oral Antibiotic + Topical Combination Therapy** BP + Antibiotic or Retinoid + BP or Retinoid + BP + Antibiotic -or- Oral Isotretinoin
Alternative Treatment
Add Topical Retinoid or BP (if not on already) -or- Consider Alternate Retinoid -or- Consider Topical Dapsone	Consider Alternate Combination Therapy -or- Consider Change in Oral Antibiotic -or Add Combined Oral Contraceptive or Oral Spironolactone (females) -or- Consider Oral Isotretinoin	Consider Change in Oral Antibiotic -or Add Combined Oral Contraceptive or Oral Spironolactone (females) -or- Consider Oral Isotretinoin

** indicates that the drug may be prescribed as a fixed combination product or as separate component