Table 1.

Sequences of Designed Stapled Peptides and Their Conversion Yields of RCM Reactions

peptide	sequence	conversion [%]a)
3	Ac-cAIIcILQQLLFIHFRIG-NH2	83
4	Ac-EcIIRcLQQLLFIHFRIG-NH2	86
5	Ac-EAcIRIcQQLLFIHFRIG-NH2	89
6	Ac-EAIcRILcQLLFIHFRIG-NH2	85
7	Ac-EAIIcILQcLLFIHFRIG-NH2	94
8	Ac-EAIIRcLQQcLFIHFRIG-NH2	97
9	Ac-EAIIRIcQQLcFIHFRIG-NH2	96
10	Ac-oAIIoILQQLLFIHFRIG-NH2	19
11	Ac-EoIIRoLQQLLFIHFRIG-NH2	57
12	Ac-EAoIRIoQQLLFIHFRIG-NH2	50
13	Ac-EAIoRILoQLLFIHFRIG-NH2	trace
14	Ac-EAIIoILQoLLFIHFRIG-NH2	9
15	Ac-EAIIRoLQQoLFIHFRIG-NH2	20
16	Ac-EAIIRIoQQLoFIHFRIG-NH2	trace

^a)Determined by peak areas in reverse phase HPLC after deprotection and cleavage from resins.