TABLE.

Familial Pediatric Clear Cell Meningioma With Germline SMARCE1 Mutation Cases Around the World

Publication (Author Name, Country, Year)	Patients (Age/Age Range in Years)	Location of Tumor	Pathology (Microscopy, Molecular)	Comments
Smith MJ et al, United Kingdom, 2013 (2)	6 (15–27)	Spinal	CCM; SMARCE1 loss in tumor in 2 patients	4 families with germline SMARCE1 mutation in all patients.
Raffalli-Ebezant et al, United Kingdom, 2015 (3)	1 (14)	CP angle	CCM, SMARCE1 loss in tumor and germline	First reported case; mother with same germline mutation and has suspected spinal meningiomas (nonbiopsied).
Smith MJ et al, United Kingdom, 2014 (4)	4 (2–30)	1 cranial, 4 spinal	CCM, SMARCE1 loss in tumor in 2 patients	SMARCE1 germline mutation in all patients, related to CCM histology, not tumor location. Incomplete penetrance of disease in males.
Gerkes EH et al, The Netherlands, 2016 (7)	2 (10, 36)	CP angle, spine	CCM, SMARCE1 loss in tumor and germline in 1 patient	Paternal grandmother at age 36 had spinal CCM, dad carrier of SMARCE1 germline mutation.
Inoue T et al, Japan, 2018 (6)	3 (5, 8, 34)	Spinal, CP angle	CCM, SMARCE1 loss in tumor in 1 patient	SMARCE1germline mutation in all 3 patients who were part of single family.
Navalkele P et al, United States	2 (6, 25)	CP angle	CCM, SMARCE1 loss in tumor and germline in both patients	Recurrent tumor; young mother with same tumor.