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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Ann Surg. 2021 Nov 1;274(5):e425–e434. doi: 10.1097/SLA.0000000000003647

Table 1:

Clinicopathological characteristics of patients in each of the clinical cohorts

Testing cohort Validation cohort Performance evaluation cohort P Value

Variable number number number
Gender Male 40 62 158
Female 25 23 46 0.04
Age at operation median (range) 69 (18-90) 70 (25-92) 69 (20-88) 0.7
Macroscopical type type1, 2 31 43 100
type3,4 34 42 104 0.94
Tumor size (mm) median (range) 55 (12-170) 55 (10-120) 55 (15-180) 0.21
Histological type intestinal 27 48 76
Diffuse 38 37 128 0.01
T factor T2 12 20 40
T3 14 35 59
T4 39 30 105 0.03
Lymph node metastasis Negative 21 29 59
Positive 44 56 145 0.66
UICC Stage 1B 8 16 23
2 15 26 47
3 18 17 69
4 24 26 65 0.2
Lymphatic invasion Negative 5 36 20
Positive 60 49 184 <0.0001
Venous invasion Negative 26 14 67
Positive 39 71 137 0.004