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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Ann Surg. 2021 Nov 1;274(5):e425–e434. doi: 10.1097/SLA.0000000000003647

Table 2:

Multivariate logistic regression analysis for the diagnosis of peritoneal metastasis in gastric cancer patients in each cohort

Univariate analysis Multivariate analysis

Variable OR 95%CI P-value OR 95%CI P-value
Testing cohort
Age ≧ 69 1.87 0.57-6.82 0.31
Male 1.16 0.35-4.24 0.81
Macroscopical type 3 or 4 7.91 1.91-54.27 0.003 6.83 1.45-50.61 0.01
Tumor size >55mm 2.19 0.66-7.99 0.2
Poorly differentiated histology 2.05 0.60-8.28 0.26
MiRNA combined signature high risk 13.12 3.12-90.96 0.0002 11.74 2.61-84.97 0.0008

Validation cohort
Age ≧ 70 0.54 0.15-1.72 0.3
Male 1.44 0.40-6.84 0.6
Macroscopical type 3 or 4 4.73 1.34-22.26 0.01 4.97 1.20-26.99 0.03
Tumor size >55mm 4.73 1.34-22.26 0.01 6.63 1.62-35.88 0.007
Poorly differentiated histology 2.76 0.86-9.80 0.09
MiRNA combined signature high risk 14.15 2.60-263.78 0.0007 17.52 2.89-343.90 0.0007

Performance evaluation cohort
Age ≧ 69 1.48 0.77-2.88 0.24
Male 0.81 0.38-1.77 0.58
Macroscopical type 3 or 4 5.82 2.74-13.59 <0.0001 6.44 2.76-16.51 <0.0001
Tumor size >55mm 3.25 1.64-6.72 0.0006 2.24 1.03-5.01 0.04
Poorly differentiated histology 2.31 1.13-5.07 0.02 1.73 0.76-4.17 0.19
MiRNA combined signature high risk 3.56 1.82-7.09 0.0002 5.22 2.42-11.80 <0.0001

OR, Odds Ratio; CI, Confidence Interval. Bold indicates a statistically significant.