Table 3.
Sensitivity, specificity, positive predicative value (PPV) and negative predicative value (NPV) for the most commonly used cut-off values for the scoring systems. 95% confidence intervals in brackets. NEWS2 is showed with three different cut off values.
| Sensitivity % (95% CI) | Specificity % (95% CI) | PPV % (95% CI) | NPV% (95% CI) | |
|---|---|---|---|---|
| qSOFA ≥ 2 | 26 (13–43) | 95 (89–98) | 59 (37–78) | 82 (78–84) |
| SIRS ≥ 2 | 79 (63–90) | 52 (43–61) | 32 (27–38) | 90 (82–94) |
| CURB-65 ≥ 2 | 58 (41–74) | 80 (71–86) | 45 (35–56) | 87 (82–91) |
| PSI ≥ 3 | 71 (54–85) | 70 (62–78) | 41 (33–49) | 89 (83–93) |
| NEWS2 ≥ 5 | 82 (66–92) | 60 (51–68) | 37 (32–43) | 92 (85–96) |
| NEWS2 ≥ 6 | 76 (60–89) | 72 (63–79) | 44 (36–52) | 91 (85–94) |
| NEWS2 ≥ 7 | 66 (49–80) | 83 (76–89) | 53 (42–64) | 89 (84–93) |
| PaO2/FiO2 ≤ 300 mmHg (≤40 kPa) | 70 (53–84) | 73 (63–81) | 49 (40–59) | 87 (80–92) |