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. 2020 Oct 21;6(43):eaba3760. doi: 10.1126/sciadv.aba3760

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 4 — All identified detoxifying enzymes were used to construct a diagnostic model for prediction of ASD status by random forest classifiers with 1000 bootstrap replicates. (A) ROC analysis of the performance of the diagnostic model. (B) Mean contributions of each detoxifying enzyme based on 1000 bootstrap replicates. (C) Dysfunction scores of the microbial detoxification inferred from the diagnostic model for samples in each quartile of patients divided according to their clinical ASD rating scores.