Table 1. Clinical and procedural characteristics of patients with duodenal perforation attributable to biliary stent migration.
Patient, age (Years), Gender | Indication for ERCP | Pancreatobiliary Diagnosis | ERCP Findings | Pancreatobiliary Stents Used (Stent Diameter, Stent Length) | Time to Perforation Identification (Days Post-ERCP) | Location | Treatment of Perforation | Potential Risk Factors |
#1, 58, female | Abdominal pain, biliary stent exchange | Post-cholecystectomy biliary stricture | Common hepatic duct stricture | 10 Fr, 9 cm plastic biliary stent in right hepatic duct 10 Fr, 11 cm plastic biliary stent in left hepatic duct 1 |
19 | Retroperitoneal | Stent removal Endoscopic clip (3) closure Percutaneous drain for retroperitoneal abscess |
Chronic rheumatoid arthritis on immunosuppressive therapy (methotrexate, infliximab, prednisone); periampullary diverticulum |
#2, 40, male | Jaundice, CT abnormality | Metastatic abdominal desmoplastic small round cell tumor with biliary obstruction | Common hepatic duct stricture |
10 Fr, 15 cm plastic biliary stent in left hepatic duct, groomed
1
10 Fr, 12 cm plastic biliary stent in right hepatic duct |
2 | Peritoneal | Stent removal Nasoduodenal suction and bowel rest Percutaneous drain for abdominal abscess |
History of radiation and ongoing chemotherapy with pazopanib; cancer |
#3, 88, female | Jaundice | Pancreatic adenocarcinoma with biliary obstruction | Distal common bile duct stricture | 10 mm, 6 cm uncovered metal biliary stent in common bile duct 10 mm, 4 cm uncovered metal biliary stent placed 11 months later, within interstices of first (migrated) stent due to tumor ingrowth 1 |
1 | Peritoneal + Retroperitoneal | Nasogastric suction and bowel rest Venting gastrostomy |
Elderly; cancer |
#4, 86, female | Jaundice, CT abnormality | Cholangiocarcinoma | Common hepatic duct stricture |
8.5 Fr, 15 cm plastic biliary stent in left hepatic duct
1
7 Fr, 15 cm plastic biliary stent in right hepatic duct |
2 | Retroperitoneal | Stent removal Endoscopic clip (3) closure |
Elderly; cachexia with recent weight loss; cancer |
#5, 71, female | Jaundice | Metastatic pancreatic cancer with biliary obstruction | Distal common bile duct stricture + right main intrahepatic stricture | 7Fr, 12 cm plastic biliary stent in right hepatic duct 1 | 14 | Not defined | Stent removal Endoscopic clip (2) closure |
Elderly; cancer |
#6, 48, male | Cholangitis | Necrotizing pancreatitis | Common bile duct stricture |
10Fr, 12 cm plastic biliary stent in common hepatic duct
1
10Fr, 10 cm plastic biliary stent in common hepatic duct |
7 | Retroperitoneal | Laparotomy | Severe duodenal edema; 5-month hospitalization with critical illness |
#7, 61, female | Jaundice | Primary sclerosing cholangitis | Multifocal intra and extrahepatic biliary strictures |
7Fr, 18 cm plastic biliary stent in left intrahepatic duct
1
7Fr, 15 cm plastic biliary stent in right intrahepatic duct |
70 | Retroperitoneal | Stent removal Endoscopic clip (4) closure |
|
#8, 90, male | Cholangitis | Cholangiocarcinoma | Left main intrahepatic bile duct stricture | 7 Fr, 13-cm plastic biliary stent in left hepatic duct 1 | 46 | Not Defined | Stent removal Endoscopic clip (2) closure |
Elderly; cancer |
#9, 56, male | Jaundice, MRCP abnormality | Metastatic cholangiocarcinoma | Bismuth IV hilar stricture |
10 Fr, 18-cm plastic biliary stent in left intrahepatic duct
1
7 Fr, 15 cm plastic biliary stent in right intrahepatic duct |
47 | Retroperitoneal | Stent removal Over-the-scope clip (OTSC) balloon to sweep sludge/pus |
Cancer; on chemotherapy |
#10, 52, male | Jaundice | Cholangiocarcinoma | Bismuth IV hilar stricture | 10 Fr, 15-cm plastic transpapillary biliary stent in left hepatic duct 7 Fr, 13-cm plastic transpapillary biliary stent in right anterior hepatic duct 1 7 Fr, 13-cm plastic biliary stent in right posterior hepatic duct |
102 | Not Defined | Stent removal Endoscopic clip (3) closure |
Cancer; on chemotherapy; chronic alcoholic |
#11, 88, male | Jaundice | Metastatic gallbladder cancer with biliary obstruction | Common hepatic duct stricture | 10 Fr, 9-cm plastic transpapillary biliary stent in right intrahepatic duct 10 Fr, 15-cm plastic transpapillary biliary stent in left intrahepatic duct 1 |
101 | Retroperitoneal | Stent removal Endoscopic clip (2) closure |
Elderly; cancer; on chemotherapy |
Biliary stent causing perforation (in bold)