Table 2.
Associations between PET parameters and outcome of NAC
| Characteristic | 40% of ΔSUVmax |
p-value | |
|---|---|---|---|
| Responder (n=17) | Non-responder (n=23) | ||
| CA-125 level before IDS | |||
| < 35 U/mL | 13 (76.5) | 9 (39.1) | 0.019 |
| ≥ 35 U/mL | 4 (23.5) | 14 (60.9) | |
| Response rate before IDSa) | |||
| CR | 3 (17.6) | 0 | 0.069 |
| PR | 14 (82.4) | 23 (100) | |
| Residual disease after IDS | |||
| NGR | 12 (70.6) | 7 (31.8) | 0.025 |
| > 0 cm | 5 (29.4) | 15 (68.2) | |
| Unknown | 0 | 1 | |
| CRS | |||
| 1 or 2 | 8 (47.1) | 21 (91.3) | 0.003 |
| 3 | 9 (52.9) | 2 (8.7) | |
Values are presented as number (%). PET, positron emission tomography; NAC, neoadjuvant chemotherapy; SUVmax, maximum standardized uptake value; CA-125, cancer antigen-125; IDS, interval debulking surgery; CR, complete response; PR, partial response; NGR, no gross residual disease; CRS, chemotherapy response score.
a)
According to the Response Evaluation Criteria in Solid Tumors [22].