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. 2020 May 25;52(4):1162–1177. doi: 10.4143/crt.2020.138

Fig. 5.

Fig. 5.

The mechanism of fibroblast growth factor receptor 4 (FGFR4)-Arg388 influencing the oncogenic properties of gastric cancer cells. (A, B) Western blot detection of the expression of related molecules including FGFR4, signal pathway (STAT3), and epithelial to mesenchymal transition (E-cadherin and vimentin) in SGC7901 and BGC803 cells with different FGFG4 genotypes (mock, normal control [NC], Gly388, and Arg388). (C, D) The changes of related molecules between overexpression Gly388- and Arg388-transfected cells were detected, when cells were incubated with the Jak2 inhibitor AG490 to block STAT3 activation.