Fig. 6. Effect of PAT-ectomy on body weight and, hepatic and pancreatic ectopic lipid deposition and gene expression after 16-week HFD feeding in male mice.

a Body weight, b pancreas weight, c pancreatic triglyceride content, and d pancreatic gene expression in PAT-ectomized and sham control mice (n = 8–10 mice/group). e Average pancreatic islet area in PAT-ectomized and sham control mice and representative H&E sections (n = 3–4 mice/group). f Liver weight, g hepatic triglyceride content, h hepatic lipid droplet distribution and representative H&E section (n = 4–6 mice/group), and i hepatic gene expression in PAT-ectomized and sham control mice (n = 8–10 mice/group). All values are expressed as mean ± SEM. *p < 0.05 and **p < 0.01.