Regardless of sex, HIV+ participants had significantly poorer performance in the Fluency (p=0.008), Processing Speed (p=0.006), Attention / Working Memory (p=0.007) domains than HIV-seronegative participants. In addition, across all participant groups, HIV+ women had the lowest Z-scores in all cognitive domains, especially the Sensorimotor (interaction-p=0.007 for dominant hand, p=0.039 for non-dominant hand), Fluency (interaction p=0.097) and Attention/Working Memory (interaction p=0.06) domains. Error bars=Standard Errors.