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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Bioorg Med Chem Lett. 2020 Aug 19;30(21):127509. doi: 10.1016/j.bmcl.2020.127509

Table 1.

MIC (μg/mL) values for ALB (1) and its corresponding analogs against S. aureus (UAMS-1) and (USA-300).

Compounds MIC (μg/mL) S. aureus
UAMS-1 (MSSA) USA300 (MRSA)
ALB (1) 2 2
Cineromycin (5) 8–16 4
6 1–4 1
7 >256 ND
9 32 ND
10 32 ND
11 128 ND
12 >256 >256
15 (major) 128 256

Inline graphic Equipotent with ALB (1)

Inline graphic More potent than ALB (1)

*

ND = Not Determined