Figure 1.

Analytical Pipeline for Driver Prediction. (A) - Example of sustained AF episode maintained by reentrant driver, which was recorded simultaneously by clinical MEM (Higher-Density (HD) and Lower-Density (LD) catheters) and high-resolution NIOM (Cameras 1–2). (B) - Ground-truth labels for electrodes (red – center of driver, blue – non-driver) were acquired by NIOM, driver periphery labels (red/blue) were counted as driver in center plus periphery annotation or as non-driver in driver center annotation. (C) - Fourier spectra of annotated unipolar HD electrograms and co-located NIOM OAPs were used for generation of frequency features for Machine Learning approach. LAA/RAA = Left/Right Atria Appendage, I/SVC = Inferior/Superior Vena Cava, MEM = Multi-Electrode Mapping, NIOM = Near-Infrared Optical Mapping, OAP = Optical Action Potential, A.U. = Arbitrary Units.