Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 21;10:17889. doi: 10.1038/s41598-020-74838-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

CTGF regulates protein expression of potential drivers of invasion and EMT-markers. (A) Relative quantification of ZEB1, CDH1, SNAI2 and VIM protein expression in mesenchymal transformed MCF-7-EMT and MDA-MB-231 breast cancer cells in comparison to MCF-7 breast cancer cells. Data represent mean ± SEM. n = 3 using one-way ANOVA with F = 39.31 and a Dunnett ‘s multiple comparison test with no matching or pairing between groups. *P < 0.05; ****P < 0.0001 (B) Relative quantification of ZEB1, CDH1 and SNAI2 protein expression in MCF-7 cells treated with rhCTGF. Data represent mean ± SEM. n = 3 using one-way ANOVA with F = 3.123 and a Dunnett ‘s multiple comparison test with no matching or pairing between groups. (C) Relative quantification of ZEB1, CDH1, SNAI2 and VIM protein expression in mesenchymal transformed breast cancer cells (MCF-7-EMT) treated transiently with CTGF siRNA for 48 h. Data represent mean ± SEM. n = 3 using one-way ANOVA with F = 2.191 and a Dunnett ‘s multiple comparison test with no matching or pairing between groups.