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. 2020 Oct 21;10:17950. doi: 10.1038/s41598-020-74837-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in the proportion of mesenteric lymph node lymphocytes compared to the sedentary group. Main lymphocyte subsets (a); Tαβ/B lymphocytes ratio (b); main Tαβ subsets (c); Th/Tc ratio (d) and Treg proportion (e). SED sedentary rats, T trained rats, TE T rats with an additional final exhaustion test, TE24 TE rats 24 h after the additional final exhaustion test. Data are expressed as mean ± SEM (n = 8). Statistical differences (one-way ANOVA followed by post-hoc Tukey test for (a,b) and Kruskal–Wallis followed by Mann–Whitney U test for c–e): *p < 0.05 vs SED group; ^фp < 0.05 vs T group; ^λp < 0.05 vs TE group.