Beas2b cells with 20,000 cells per seahorse well were grown to 90% confluency. Immediately after serum deprivation, the wells were exposed to a three-session exposure to JUUL Virginia Tobacco pods with 12-hour intervals between sessions. (A) Immediate post final exposure graphs of oxygen consumption rate and extracellular acidification rate. (B) Immediate post final exposure values for mitochondrial respiration. * p < 0.05, or ** p < 0.01 vs air exposed, unpaired t-test N = 6 wells per group. (C) 24 hours post final exposure graphs of oxygen consumption rate and extracellular acidification rate. (D) 24 hours post final exposure values for mitochondrial respiration. *** p < 0.001 vs air exposed, unpaired t-test N = 4–6 wells per group.